Title: Beneficial Hypothermia

Writer: Padmaja Durga, Additional Professor, Department of Anesthesiology and Intensive Treatment, Nizam's Institute of Medical Sciences, Hyderabad, A. P., India. Summary:

Therapeutic hypothermia has been recommended for neuroprotection in cardiac arrest-induced encephalopathy, neonatal hypoxic-ischemic encephalopathy, disturbing brain harm, stroke, hepatic encephalopathy, and spinal cord injury, and as a great adjunct to aneurysm surgery. From this review, we all address physiological mechanism of hypothermia to mitigate neurological injury, the trials which have been performed for each of these signals, the strength of the evidence to support treatment with mild/moderate hypothermia. Proof is strongest for prehospital cardiac arrest and neonatal hypoxic-ischemic encephalopathy. To get traumatic human brain injury, a recent meta-analysis suggests that cooling may possibly increase the probability of a good result, but would not change fatality rates. For several of the other signs, such as heart stroke and spine injury, tests are regular, but the info is not enough to suggest routine make use of hypothermia currently. Although activated hypothermia is apparently a highly encouraging treatment, it ought to be emphasized that it must be associated with a number of potentially critical side effects, which might negate several or most of its potential benefits. Reduction and/or early treatment of these kinds of complications are definitely the key to powerful use of hypothermia in clinical practice. Keywords and phrases: Therapeutic Hypothermia, mechanism, specialized medical application, facts, cooling strategies, practical aspects.

Section Titles



Mechanisms root neuroprotective associated with Hypothermia Potential clinical applications of hypothermia

Physiological, Metabolic and cellular effects of hypothermia Functional Aspects of A



Hypothermia continues to be used for medicinal purposes since olden times. It has been used to provide...